Siim Land Podcast

#155 Life Extension Through Diet with James Clement

December 31, 2019

What kind of diets help you to live longer and fight disease? Well, in my opinion, it's more about when you eat and how much rather than what you eat and research in life-extension is showing that to be the case too.

Welcome to the Body Mind Empowerment podcast I’m your host Siim Land and our guest today is James Clement. James is a lawyer and entrepreneur turned research scientist who works on life extension. He’s best known for his 2010 supercentenarian research study and was the world’s 12th person to have his whole genome sequenced.


  • How James Went From Being a Lawyer to Life Extension Research 01:30
  • What Do Supercentenarians Have in Common 07:45
  • The Switch for Turning On Longevity Genes 10:05
  • Calorie Restriction vs Ketosis vs Autophagy 16:50
  • Degrees of Autophagy and mTOR 22:00
  • Don't Combine Fats and Carbs Together 31:55
  • Does Eating Meat Accelerate Aging 38:10
  • How Does James Do Intermittent Fasting 48:00
  • Biomarkers for Measuring Aging and Autophagy 57:16

And much more...

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